Whole30 / Paleo Mississippi Pot Roast
If you’re looking for a comforting meal that warms the soul, this Whole30 / Paleo Mississippi Pot Roast is just what you need. With its rich flavors and tender beef, it’s a dish that truly feels like a hug in a bowl. I love making this on busy weeknights or for family gatherings because it requires minimal effort while delivering maximum flavor. Plus, it’s a great way to enjoy wholesome ingredients without sacrificing taste!
This recipe has become a favorite in my household, and I’m excited to share it with you! It’s perfect for those who follow Whole30 or Paleo diets, but honestly, everyone will love it regardless of their eating habits.
Why You’ll Love This Recipe
- Easy preparation: Simply sear the meat and let your slow cooker do the rest. You can set it and forget it!
- Family-friendly appeal: This hearty pot roast is sure to please both kids and adults alike. It’s comfort food at its best!
- Meal prep friendly: Cook once and enjoy leftovers throughout the week. It tastes even better the next day!
- Delicious flavor: The combination of spices and pepperoncini gives this dish a unique kick that keeps everyone coming back for more.

Ingredients You’ll Need
Gathering ingredients for this Whole30 / Paleo Mississippi Pot Roast is simple! All you need are some wholesome, clean ingredients that come together beautifully in the slow cooker. Here’s what you’ll need:
For the Roast
- 3-5 lb beef chuck roast
- 2 tbsp olive oil
- 1 cup beef broth
- 1 tbsp dried chives
- 2 tsp garlic powder
- 2 tsp onion powder
- 1 tsp dried dill
- 1 tsp salt
- 1 tsp black pepper
- 6-8 pepperoncini peppers, whole
- 1-2 tbsp pepperoncini pepper juice (from the jar)
- 4 tbsp ghee
Variations
One of the best things about this recipe is its flexibility! You can easily adjust it based on what you have on hand or your specific taste preferences.
- Swap the protein: Try using chicken thighs or brisket if you’re in the mood for something different.
- Add veggies: Toss in some carrots or potatoes during cooking for a complete meal in one pot.
- Spice it up: If you enjoy heat, add some crushed red pepper flakes or jalapeños to give it an extra kick.
- Herb substitutions: Feel free to get creative with herbs! Fresh thyme or rosemary can add a delightful touch.
How to Make Whole30 / Paleo Mississippi Pot Roast
Step 1: Prepare the Chuck Roast
Start by taking your chuck roast out of the fridge. Pat it dry with paper towels and generously season all sides with salt and pepper. This step is crucial because seasoning ensures every bite is packed with flavor. Heat a couple of tablespoons of olive oil in a large skillet over medium-high heat until shimmering. Searing the meat for 1-2 minutes per side creates that beautiful golden crust, enhancing both texture and taste.
Step 2: Deglaze the Pan
Once you’ve seared your chuck roast, remove it from the skillet and add 1 cup of beef broth to deglaze the pan over medium-high heat. Bring it to a boil while scraping up all those delicious brown bits from the bottom. This step adds depth of flavor to your pot roast and takes just a few minutes to complete!
Step 3: Assemble in the Slow Cooker
Pour that flavorful liquid over your chuck roast placed in the slow cooker. Sprinkle dried chives, garlic powder, onion powder, dill, salt, and pepper over everything. Arrange your whole pepperoncini peppers around the meat and drizzle in some juice from their jar. Topping it all off with ghee gives richness to each bite as it melts into the meat during cooking.
Step 4: Let It Cook
Cover your slow cooker with a lid and set it to cook on low for 8-10 hours or high for 5-6 hours. The long cooking time allows flavors to meld beautifully while making that beef fork-tender. If after cooking time your roast still feels tough, simply cover again and give it another hour—trust me; it’s worth waiting for!
Step 5: Serve & Enjoy
When it’s done cooking, serve your Whole30 / Paleo Mississippi Pot Roast over mashed potatoes, polenta, rice, or even enjoy it solo! This dish not only fills you up but leaves everyone asking for seconds.
Enjoy every bite of this delightful meal!
Pro Tips for Making Whole30 / Paleo Mississippi Pot Roast
Creating a perfectly flavorful and tender Mississippi Pot Roast is easier than you think! Here are some tips to enhance your cooking experience.
- Choose the right cut of meat: A beef chuck roast is ideal because it has enough marbling and connective tissue, which breaks down during slow cooking to create a melt-in-your-mouth texture.
- Sear the meat for flavor: Don’t skip the searing step! It adds a depth of flavor that enhances the overall dish. The caramelized bits that form in the pan are packed with taste, so make sure to deglaze properly!
- Let it rest before serving: After cooking, allow your pot roast to rest for about 10-15 minutes before slicing. This helps retain the juices, keeping every bite moist and delicious.
- Adjust spice levels to taste: Feel free to tweak the seasonings and peppers based on your preferences. If you like it spicier, add more pepperoncini or incorporate some crushed red pepper flakes.
- Use leftovers creatively: This pot roast makes incredible leftovers! Use it in salads, wraps, or even as a filling for stuffed peppers. The flavors only get better with time!
How to Serve Whole30 / Paleo Mississippi Pot Roast
Serving your Whole30 / Paleo Mississippi Pot Roast can be just as delightful as making it! Here are some ideas to present this hearty dish beautifully.
Garnishes
- Fresh herbs: A sprinkle of chopped fresh parsley or cilantro adds a pop of color and freshness that brightens up the rich flavors.
- Chili flakes: For those who enjoy a little heat, a dash of chili flakes can bring an exciting kick to each bite.
Side Dishes
- Mashed Cauliflower: Creamy mashed cauliflower serves as a wonderful low-carb alternative to traditional mashed potatoes. It absorbs all the delicious juices from the pot roast!
- Roasted Vegetables: A medley of seasonal veggies roasted until caramelized complements the rich flavors of the pot roast, adding both nutrition and color to your plate.
- Zucchini Noodles: Light and refreshing, zucchini noodles offer a great textural contrast while keeping your meal compliant with Whole30 standards.
- Rice or Quinoa: For those who prefer grains, serving this pot roast over fluffy rice or quinoa can provide a satisfying base that soaks up all those delicious juices.
Enjoy preparing and sharing this comforting meal with loved ones – it’s sure to be a hit at any dinner table!

Make Ahead and Storage
This Whole30 / Paleo Mississippi Pot Roast is perfect for meal prep, making it easy to enjoy healthy meals throughout the week. The flavors deepen as it sits, so it’s a fantastic option for leftovers!
Storing Leftovers
- Allow the pot roast to cool completely before storing.
- Place the leftovers in an airtight container.
- Store in the refrigerator for up to 4 days.
Freezing
- Slice or shred the leftover pot roast before freezing for easier portioning.
- Place in freezer-safe containers or bags, removing as much air as possible.
- Freeze for up to 3 months. For best quality, label with the date.
Reheating
- Thaw frozen pot roast overnight in the refrigerator before reheating.
- Reheat in a skillet over low heat until warmed through, adding a splash of beef broth if needed.
- Alternatively, microwave in short bursts, stirring occasionally until hot.
FAQs
Here are some common questions about this recipe!
Can I make Whole30 / Paleo Mississippi Pot Roast without a slow cooker?
Yes! You can adapt this recipe to your oven by using a Dutch oven. Simply sear the meat as directed, add the ingredients, and cover. Cook at 275°F (135°C) for about 3-4 hours or until fork tender.
Is Whole30 / Paleo Mississippi Pot Roast good for meal prep?
Absolutely! This dish is perfect for meal prep since it stores well and tastes even better after a day or two in the fridge. Enjoy it over various sides throughout the week!
What can I serve with Whole30 / Paleo Mississippi Pot Roast?
You can serve this delicious pot roast over mashed potatoes, polenta, rice, or mashed cauliflower. It’s also delightful on its own!
Final Thoughts
I hope you find joy in making this Whole30 / Paleo Mississippi Pot Roast! It’s not just a meal; it’s an experience filled with warmth and comfort. Whether you’re enjoying it on a busy weeknight or sharing it with family on a cozy Sunday dinner, this recipe is sure to be a hit. I can’t wait for you to try it—happy cooking!
Whole30 / Paleo Mississippi Pot Roast
If you’re in search of a comforting and nutritious meal, look no further than this Whole30 / Paleo Mississippi Pot Roast. This dish features tender beef infused with rich flavors from spices and pepperoncini, making it the perfect cozy dinner option for busy weeknights or family gatherings. Simply sear the meat, throw everything into your slow cooker, and let it work its magic while you go about your day. With minimal effort and maximum flavor, this wholesome recipe will leave everyone at the table asking for seconds!
- Prep Time: 15 minutes
- Cook Time: 8 hours
- Total Time: 8 hours 15 minutes
- Yield: Serves approximately six people 1x
- Category: Main
- Method: Slow Cooker
- Cuisine: American
Ingredients
- 3–5 lb beef chuck roast
- 2 tbsp olive oil
- 1 cup beef broth
- 1 tbsp dried chives
- 2 tsp garlic powder
- 2 tsp onion powder
- 1 tsp dried dill
- 1 tsp salt
- 1 tsp black pepper
- 6–8 whole pepperoncini peppers
- 1–2 tbsp pepperoncini juice
- 4 tbsp ghee
Instructions
- Pat the chuck roast dry, season generously with salt and pepper, and sear in olive oil over medium-high heat until golden brown on all sides.
- Deglaze the pan with beef broth, scraping up any browned bits for added flavor.
- In a slow cooker, place the seared roast and pour the deglazed liquid over it. Add spices, whole pepperoncini, and drizzle with ghee.
- Cook on low for 8-10 hours or high for 5-6 hours until fork-tender.
- Let rest before slicing and serve over mashed cauliflower or enjoy solo.
Nutrition
- Serving Size: Approximately 5 oz (142g)
- Calories: 375
- Sugar: 0g
- Sodium: 550mg
- Fat: 25g
- Saturated Fat: 10g
- Unsaturated Fat: 15g
- Trans Fat: 0g
- Carbohydrates: 3g
- Fiber: 0g
- Protein: 36g
- Cholesterol: 120mg
